Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27472886 | 0.86 | SLC2A1 (0.40) | SLC2A1IGF1RHTTTSHRPKM | |
| Hydrochloric Acid SCHEMBL27546093 | 0.77 | CRHR1 (0.45) | — | |
| SCHEMBL6980587 | 0.71 | LMNA (0.44) | HTTTSHRPKMCRHBPPIK3CB | |
| SCHEMBL6981234 | 0.68 | CRHR1 (0.40) | SLC2A1HTTTSHRPKMCRHBP | |
| Hydrochloric Acid SCHEMBL6985578 | 0.68 | CRHR1 (0.67) | — | |
| Hydrochloric Acid SCHEMBL27475047 | 0.64 | CRHR1 (0.46) | MAPTKDM4E | |
| SCHEMBL6998839 | 0.63 | GRIN2D (0.55) | SLC2A1MAPTMAPK1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6996304 | 0.62 | GRIN2D (0.54) | SLC2A1MAPTMAPK1ALDH1A1MEN1 | |
| SCHEMBL12485985 | 0.61 | MAPT (0.47) | SLC2A1IGF1RHTTTSHRMAPT | |
| SCHEMBL16244801 | 0.60 | SLC2A1 (0.64) | SLC2A1HTTTSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142931-C | 4-tetrahydropyridylpyrimidine derivatives | ������ҩ��ʽ���� | 2004-03-24 | — | — | CN | disclosed |
| CN-1257491-A | 4-tetrahydropyridylpyrimidine derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2000-06-21 | — | — | CN | disclosed |