Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292166 | 0.78 | LMNA (0.38) | GAAKDM4EMTNR1ASIRT2SIRT1 | |
| SCHEMBL3078629 | 0.78 | KDM4E (0.39) | GAAKDM4EMTNR1ASIRT2SIRT1 | |
| Urea SCHEMBL27986443 | 0.77 | KDM4E (0.50) | GAAKDM4EMTNR1ASIRT2SIRT1 | |
| SCHEMBL6793982 | 0.76 | KDM4E (0.48) | GAAKDM4EMTNR1ASIRT2SIRT1 | |
| SCHEMBL27661025 | 0.76 | MAPT (0.46) | GAAKDM4ESIRT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9332916 | 0.76 | TSHR (0.42) | GAAKDM4EMTNR1ASIRT1ALDH1A1 | |
| SCHEMBL27837285 | 0.75 | APOBEC3G (0.52) | GAAKDM4EMTNR1ASIRT1ALDH1A1 | |
| SCHEMBL7265932 | 0.75 | IFNAR1 (0.43) | GAAKDM4ESIRT2SIRT1SIRT3 | |
| SCHEMBL4206138 | 0.74 | POLB (0.43) | GAAKDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL27574868 | 0.74 | ALDH1A1 (0.42) | GAAALDH1A1SMN1; SMN2POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1181070-C | Urea substituted imidazoquinolines | 3M | 2004-12-22 | — | — | CN | claimed |
| CN-103159695-A | Thiazole compound capable of restraining human immunodeficiency virus (HIV) replication and effective against drug-resistant HIV virus strains and preparation method and purpose thereof | UNIV CAPITAL NORMAL | 2013-06-19 | — | — | CN | disclosed |
| CN-101053823-A | Poly (m-phenylene diamine) used as mercury ion adsorbent | UNIV TONGJI (CN) | 2007-10-17 | — | — | CN | disclosed |
| CN-1229360-C | Preparation method of 2-(hydrocarbon) imido (amine)-4-thiazolidone | UNIV CHINA PHARMA (CN) | 2005-11-30 | — | — | CN | disclosed |
| CN-1189330-C | Imaging media containing heat developable photosensitive microcapsule | SIPIX IMAGING INC (US) | 2005-02-16 | — | — | CN | disclosed |
| CN-1556106-A | Preparation method of 2-(hydrocarbon) imido (amine)-4-thiazolidone | 中国药科大学 | 2004-12-22 | — | — | CN | disclosed |