Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27475467 | 0.78 | GAA (0.53) | LMNARECQLSMN1; SMN2PLK1IFNAR1 | |
| SCHEMBL11292168 | 0.76 | LMNA (0.43) | LMNARECQLSMN1; SMN2PLK1IFNAR1 | |
| SCHEMBL11292167 | 0.71 | LMNA (0.41) | LMNARECQLSMN1; SMN2IFNAR1ALDH1A1 | |
| SCHEMBL2116696 | 0.68 | IFNAR1 (0.43) | LMNASMN1; SMN2IFNAR1ALDH1A1HPGD | |
| SCHEMBL11766853 | 0.68 | LMNA (0.46) | LMNARECQLSMN1; SMN2PLK1IFNAR1 | |
| SCHEMBL7357489 | 0.67 | ANPEP (0.46) | LMNARECQLSMN1; SMN2PLK1IFNAR1 | |
| SCHEMBL21694354 | 0.65 | CA12 (0.53) | LMNARECQLSMN1; SMN2PLK1IFNAR1 | |
| SCHEMBL9342243 | 0.65 | CYP1A2 (0.45) | LMNASMN1; SMN2IFNAR1ALDH1A1F2 | |
| SCHEMBL11765715 | 0.65 | POLB (0.46) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL3078629 | 0.65 | KDM4E (0.39) | LMNARECQLSMN1; SMN2PLK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311647-A | Process for preparation of (hydrocarbonthio)oxamides | THE B. F. GOODRICH COMPANY (US) | 1982-01-19 | — | — | US | disclosed |