Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ortho-Phthalaldehyde SCHEMBL7621085 | 0.86 | LMNA (0.59) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL29365160 | 0.82 | — | — | |
| SCHEMBL25505 | 0.82 | — | — | |
| SCHEMBL29776700 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL29953565 | 0.80 | LMNA (0.60) | LMNAKMT2AMEN1THRBBLM | |
| Hydrochloric Acid SCHEMBL10526696 | 0.80 | LMNA (0.60) | LMNAKMT2AMEN1THRBBLM | |
| Iodide SCHEMBL27959040 | 0.80 | LMNA (0.60) | LMNAKMT2AMEN1THRBBLM | |
| Bromide SCHEMBL28345884 | 0.80 | LMNA (0.60) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL28156648 | 0.80 | LMNA (0.60) | LMNAKMT2AMEN1THRBBLM | |
| Salicyladehyde SCHEMBL6694640 | 0.78 | TRIM24 (0.67) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1172912-C | Racemisation process for use in manufacture of levobupivacaine and related piperidinecarboxanilide anaesthetic agents | ��������ķ������ | 2004-10-27 | — | — | CN | disclosed |
| CN-1168134-A | Racemization process for the production of levobupivacaine and related piperidinecarboxanilide anaesthetics | CHIROSCIENCE LTD (GB) | 1997-12-17 | — | — | CN | disclosed |