Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832558 | 0.82 | NPSR1 (0.43) | NPSR1ALDH1A1LMNAGAATSHR | |
| SCHEMBL9724434 | 0.74 | NPSR1 (0.55) | NPSR1ALDH1A1LMNAGAATSHR | |
| SCHEMBL8871090 | 0.71 | NPSR1 (0.48) | NPSR1ALDH1A1LMNAGAATSHR | |
| SCHEMBL27512035 | 0.71 | LMNA (0.47) | NPSR1ALDH1A1LMNAGAATSHR | |
| SCHEMBL11263171 | 0.70 | ALDH1A1 (0.54) | NPSR1ALDH1A1LMNAGAAMAPK1 | |
| SCHEMBL28226781 | 0.67 | LMNA (0.56) | NPSR1ALDH1A1LMNAGAATSHR | |
| SCHEMBL28312197 | 0.67 | LMNA (0.46) | NPSR1ALDH1A1LMNAGAATSHR | |
| SCHEMBL27512034 | 0.65 | NPSR1 (0.47) | NPSR1ALDH1A1LMNAGAATSHR | |
| SCHEMBL2393621 | 0.65 | LMNA (0.57) | NPSR1ALDH1A1LMNAGAATSHR | |
| SCHEMBL13727140 | 0.64 | NPSR1 (0.80) | NPSR1ALDH1A1LMNATSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1175247-A | Steroid receptor modulator compounds and methods | LIGAND PHARM INC (US) | 1998-03-04 | — | — | CN | claimed |