SCHEMBL13727140

SCHEMBL13727140

CC1=CC(C)(C)N(C(=O)c2ccc(Br)cc2)c2ccccc21

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 7/20 0.80
TSHR P16473 4/20 0.80
MAPK1 P28482 2/20 0.80
USP2 O75604 1/20 0.80
LMNA P02545 3/20 0.63
KMT2A Q03164 2/20 0.61
MEN1 O00255 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C9 P11712 1/20 0.61
CRHBP P24387 1/20 0.61
CYP2C19 P33261 1/20 0.61
ATM Q13315 1/20 0.61
CRHR2 Q13324 1/20 0.61
ALDH1A1 P00352 7/20 0.58
MAPT P10636 3/20 0.55
KDM4E B2RXH2 2/20 0.55
MCOLN3 Q8TDD5 1/20 0.53
HTT P42858 2/20 0.47
TDP1 Q9NUW8 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8850325 0.78 LMNA (1.00) NPSR1TSHRMAPK1USP2LMNA
SCHEMBL29522421 0.78 LMNA (1.00) NPSR1TSHRMAPK1USP2LMNA
SCHEMBL13925443 0.76 NPSR1 (0.67) NPSR1TSHRMAPK1USP2LMNA
SCHEMBL28985711 0.74 ALDH1A1 (0.76) NPSR1TSHRMAPK1USP2LMNA
SCHEMBL27284117 0.73 LMNA (0.68) NPSR1TSHRMAPK1USP2LMNA
SCHEMBL11306212 0.73 LMNA (0.68) NPSR1TSHRMAPK1USP2LMNA
SCHEMBL3379896 0.70 KMT2A (0.54) NPSR1TSHRMAPK1USP2LMNA
SCHEMBL9147388 0.69 LMNA (0.79) NPSR1TSHRMAPK1USP2LMNA
SCHEMBL16992614 0.69 ALDH1A1 (1.00) NPSR1TSHRMAPK1USP2LMNA
SCHEMBL29424350 0.69 ALDH1A1 (1.00) NPSR1TSHRMAPK1USP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103648277-A Improved honeybee repellents and uses thereof INSCENT INC 2014-03-19 CN claimed
EP-2704578-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF Inscent, Inc. (US) 2014-03-12 EP claimed
WO-2012151556-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF INSCENT, INC. (US) 2012-11-08 WO claimed
US-11963527-B2 Compounds, compositions, and methods for altering insect and organism behavior BASF CORPORATION (US) 2024-04-23 US disclosed
US-20190104732-A1 Compounds, Compositions, and Methods for Altering Insect and Organism Behavior BASF CORPORATION 2019-04-11 US disclosed
US-10098352-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2018-10-16 US disclosed
US-20160330960-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2016-11-17 US disclosed
US-20160330960-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2016-11-17 US disclosed
US-20160330960-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2016-11-17 US disclosed
US-9439434-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2016-09-13 US disclosed
US-9439434-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2016-09-13 US disclosed
WO-2014146145-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR BAYER CROPSCIENCE LP (US) 2014-09-18 WO disclosed
WO-2014146143-A2 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA, ARTICLE, AND/OR STRUCTURE BAYER CROPSCIENCE LP (US) 2014-09-18 WO disclosed
US-20140155261-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2014-06-05 US disclosed
US-20140155261-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2014-06-05 US disclosed
US-20140155261-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2014-06-05 US disclosed
CN-103648277-A Improved honeybee repellents and uses thereof INSCENT INC 2014-03-19 CN disclosed
EP-2704578-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF Inscent, Inc. (US) 2014-03-12 EP disclosed
WO-2012151556-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF INSCENT, INC. (US) 2012-11-08 WO disclosed
WO-2012151556-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF INSCENT, INC. (US) 2012-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160330960-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 NPSR1 1241/4885TSHR 3237/4885MAPK1 3847/4885
US-10098352-B2 Honeybee repellents and uses thereof ACHE, AHNAK, L3MBTL3 NPSR1 1241/4885TSHR 3237/4885MAPK1 3847/4885
US-11963527-B2 Compounds, compositions, and methods for altering insect and organism behavior ACHE, DDT, MGLL NPSR1 1748/4885TSHR 2908/4885MAPK1 4396/4885
US-20140155261-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 NPSR1 1241/4885TSHR 3237/4885MAPK1 3847/4885
US-20190104732-A1 Compounds, Compositions, and Methods for Altering Insect and Organism Behavior ACHE, DDT, MGLL NPSR1 1748/4885TSHR 2908/4885MAPK1 4396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.