Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27610325 | 0.84 | KDM4E (0.48) | FTOKDM4EMAOAMAOBALDH1A1 | |
| SCHEMBL29799642 | 0.82 | FTO (1.00) | FTOKDM4EAKR1B1MAOAMAOB | |
| SCHEMBL546240 | 0.82 | FTO (1.00) | FTOKDM4EAKR1B1MAOAMAOB | |
| Ethoxycarbonyl Group SCHEMBL28786244 | 0.82 | DYRK1A (0.46) | FTOKDM4EMAOAMAOBALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28007143 | 0.82 | CHRM2 (0.41) | FTOKDM4EAKR1B1MAOAMAOB | |
| Methylene Chloride SCHEMBL27891472 | 0.81 | FTO (0.89) | FTOKDM4EAKR1B1MAOAMAOB | |
| Chromone SCHEMBL27464281 | 0.80 | MAOB (0.64) | FTOKDM4EMAOAMAOBALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27648948 | 0.79 | CYP2A6 (0.45) | FTOMAOAMAOBCA12CA2 | |
| Ethoxycarbonyl Group SCHEMBL28790188 | 0.76 | SIGMAR1 (0.44) | FTOKDM4EMAOAMAOB | |
| Ethoxycarbonyl Group SCHEMBL27596280 | 0.75 | FTO (0.35) | FTOMAOAMAOBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712648-A | Benzene-fused 6-membered oxygen-containing heterocyclic derivatives of bicyclic heteroaryls | NOVARTIS AG | 2012-10-03 | — | — | CN | disclosed |
| CN-101977505-A | Farnesoid x receptor agonists | SMITHKLINE BEECHAM CORP | 2011-02-16 | — | — | CN | disclosed |
| CN-1155590-C | Chromone compounds with antineoplastic activity and its open-loop products and preparing process | 中国药科大学 | 2004-06-30 | — | — | CN | disclosed |
| CN-1382688-A | Chromone compounds with antineoplastic activity and its open-loop products and preparing process | CHINESE PHAMACOLOGY UNIV (CN) | 2002-12-04 | — | — | CN | disclosed |