Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.64 |
| ▸ | MAOA | P21397 | 8/20 | 0.64 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chromone SCHEMBL28781288 | 0.84 | MAOB (0.72) | MAOBMAOAFTOACHEKDM4E | |
| Chromone SCHEMBL28860974 | 0.81 | MAOB (0.68) | MAOBMAOAFTOACHEKDM4E | |
| Chromone SCHEMBL27887886 | 0.80 | MAOB (0.78) | MAOBMAOAFTOACHEKDM4E | |
| Ethoxycarbonyl Group SCHEMBL28790188 | 0.80 | SIGMAR1 (0.44) | MAOBMAOAFTOACHEKDM4E | |
| Chromone SCHEMBL37994 | 0.80 | MAOA (1.00) | MAOBMAOAFTOACHEKDM4E | |
| Chromone SCHEMBL30075941 | 0.80 | MAOA (1.00) | MAOBMAOAFTOACHEKDM4E | |
| Chromone SCHEMBL28268880 | 0.80 | MAOA (1.00) | MAOBMAOAFTOACHEKDM4E | |
| Chromone SCHEMBL29369932 | 0.80 | MAOA (1.00) | MAOBMAOAFTOACHEKDM4E | |
| Chromone SCHEMBL6347379 | 0.80 | MAOA (1.00) | MAOBMAOAFTOACHEKDM4E | |
| Benzofuran SCHEMBL28100443 | 0.80 | CYP2A6 (0.39) | MAOBMAOAFTOLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641864-A | ANTI-INFECTIVE AGENTS | 邓迪大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-1155590-C | Chromone compounds with antineoplastic activity and its open-loop products and preparing process | 中国药科大学 | 2004-06-30 | — | — | CN | disclosed |
| CN-1382688-A | Chromone compounds with antineoplastic activity and its open-loop products and preparing process | CHINESE PHAMACOLOGY UNIV (CN) | 2002-12-04 | — | — | CN | disclosed |