Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27478891 | 0.99 | CNR1 (0.42) | CNR1TLR8CNR2SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL5688269 | 0.96 | CNR1 (0.37) | CNR1TLR8CNR2SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL27478889 | 0.91 | SLC6A4 (0.36) | CNR1TLR8CNR2SLC6A4DRD2 | |
| Hydrochloric Acid SCHEMBL4065888 | 0.86 | HTR7 (0.35) | CNR2SLC6A4DRD2ALOX15HTR7 | |
| Hydrochloric Acid SCHEMBL27478062 | 0.86 | CNR1 (0.33) | CNR1SLC6A4DRD2MAPT | |
| Hydrochloric Acid SCHEMBL8158890 | 0.86 | CNR1 (0.31) | CNR1 | |
| Hydrochloric Acid SCHEMBL27479672 | 0.84 | SOAT1 (0.36) | CNR1TLR8KCNH2MAPTPTPN1 | |
| Hydrochloric Acid SCHEMBL27479290 | 0.83 | CNR1 (0.33) | CNR1SLC6A4DRD2HTR7MAPT | |
| Hydrochloric Acid SCHEMBL27479668 | 0.82 | SOAT1 (0.38) | CNR1KCNH2PTPN1 | |
| SCHEMBL27492404 | 0.82 | CNR1 (0.40) | CNR1TLR8CNR2SLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1191286-C | Ethylene copolymer rubber, process for producing same and use | MITSUI CHEMICALS INC (JP) | 2005-03-02 | — | — | CN | disclosed |
| CN-1344283-A | Ethylene copolymer rubber, process for producing the same, and use thereof | MITSUI CHEMICALS INC (JP) | 2002-04-10 | — | — | CN | disclosed |