Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DDO | Q99489 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL22129336 | 0.71 | BCHE (0.32) | — | |
| SCHEMBL8525654 | 0.61 | — | — | |
| Succinic Acid SCHEMBL27888588 | 0.60 | TBXAS1 (0.34) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL15752190 | 0.60 | HPGD (0.30) | — | |
| SCHEMBL13496021 | 0.59 | NNMT (0.33) | ALDH1A1 | |
| SCHEMBL19945191 | 0.58 | — | — | |
| SCHEMBL170781 | 0.55 | — | — | |
| SCHEMBL9193351 | 0.55 | GAA (0.38) | ALDH1A1 | |
| SCHEMBL9803915 | 0.51 | KDM4E (0.50) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL2462957 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101273988-B | Treatment and prevention of neoplasms with salts of aminoimidazole carboxamide and 5-amino or substituted amino 1,2,3-triazoles | TACTICAL THERAPEUTICS, INC. (US) | 2011-12-14 | — | — | CN | disclosed |
| CN-101273988-A | Treatment and prevention of neoplasms with salts of aminoimidazole carboxamide and 5-amino or substituted amino 1,2,3-triazoles | TACTICAL THERAPEUTICS INC (US) | 2008-10-01 | — | — | CN | disclosed |
| CN-1318029-C | Use of salts of aminoimidazole carboxamides and of 5-amino or substituted amino 1,2, 3-triazoles for preparing pharmaceutical compositions for the treatment and prevention of tumors | CONSTANTIA GROUPE CORP (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1191485-A | Treatment and prevention of tumors with salts of aminoimidazole carboxamides and 5-amino or substituted amino 1,2, 3-triazoles | CONSTANTIA GROUPE CORP (AT) | 1998-08-26 | — | — | CN | disclosed |
| CN-1156144-A | Purin-6-one derivatives | BAYER AG (DE) | 1997-08-06 | — | — | CN | disclosed |