Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.53 |
| ▸ | CTSB | P07858 | 6/20 | 0.53 |
| ▸ | CTSV | O60911 | 6/20 | 0.53 |
| ▸ | CTSS | P25774 | 6/20 | 0.53 |
| ▸ | CTSK | P43235 | 6/20 | 0.53 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552211 | 1.00 | CTSL (0.53) | CTSLCTSBCTSVCTSSCTSK | |
| SCHEMBL25045736 | 0.87 | CTSL (0.52) | CTSLCTSBCTSVCTSSCTSK | |
| SCHEMBL30082819 | 0.86 | TACR1 (0.51) | CTSLCTSBCTSVCTSSCTSK | |
| SCHEMBL29981912 | 0.85 | FOLH1 (0.52) | CTSLCTSBCTSVCTSSCTSK | |
| SCHEMBL31369749 | 0.85 | CTSL (0.52) | CTSLCTSBCTSVCTSSCTSK | |
| SCHEMBL13811865 | 0.85 | L3MBTL1 (0.51) | CTSSCTSKFPR2LMNAFOLH1 | |
| SCHEMBL805207 | 0.85 | CTSL (0.52) | CTSLCTSBCTSVCTSSCTSK | |
| SCHEMBL29539732 | 0.85 | CTSL (0.52) | CTSLCTSBCTSVCTSSCTSK | |
| SCHEMBL4404729 | 0.85 | L3MBTL1 (0.51) | CTSSCTSKFPR2LMNAFOLH1 | |
| SCHEMBL16287362 | 0.85 | CTSL (0.52) | CTSLCTSBCTSVCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1160368-C | Endothelin antegon | 中国人民解放军军事医学科学院毒物药 | 2004-08-04 | — | — | CN | disclosed |
| CN-1155612-C | Endothelin antagon | 中国人民解放军军事医学科学院毒物药 | 2004-06-30 | — | — | CN | disclosed |
| CN-1155611-C | Endothelin antagon | 中国人民解放军军事医学科学院毒物药 | 2004-06-30 | — | — | CN | disclosed |
| CN-1330077-A | Endothelin antegon | INST OF TOXIC MEDICINES PLA S (CN) | 2002-01-09 | — | — | CN | disclosed |
| CN-1330076-A | Endothelin antagon | INST OF TOXIC MEDICINES PLA S (CN) | 2002-01-09 | — | — | CN | disclosed |