Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30742673 | 0.91 | USP30 (0.37) | USP30HTR2CSLC6A4HTR2BGPR119 | |
| SCHEMBL27478001 | 0.91 | USP30 (0.37) | USP30HTR2CSLC6A4HTR2BGPR119 | |
| SCHEMBL29826311 | 0.83 | LNPEP (0.42) | GPR119LNPEP | |
| SCHEMBL29826215 | 0.79 | CYP2C9 (0.44) | GPR119LNPEP | |
| SCHEMBL29826118 | 0.78 | CACNB4 (0.44) | GPR119LNPEP | |
| SCHEMBL29826391 | 0.77 | CACNB4 (0.44) | GPR119LNPEP | |
| SCHEMBL29826647 | 0.76 | GPR119 (0.47) | GPR119LNPEP | |
| SCHEMBL15538058 | 0.76 | GPR119 (0.46) | USP30GPR119ALDH1A1 | |
| SCHEMBL30745378 | 0.76 | SCN9A (0.39) | GPR119LNPEPALDH1A1SCN9AGRM5 | |
| SCHEMBL29826839 | 0.76 | PDE4A (0.43) | GPR119LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026338-A1 | N-HETEROCYLIC GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |