Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30053042 | 0.85 | CACNB4 (0.40) | SCN9ALNPEPXDHGPR119TBK1 | |
| SCHEMBL24791773 | 0.85 | CACNB4 (0.40) | SCN9ALNPEPXDHGPR119TBK1 | |
| SCHEMBL29825999 | 0.83 | LNPEP (0.37) | SCN9ALNPEPGPR119TBK1 | |
| SCHEMBL30740733 | 0.81 | ALDH1A1 (0.41) | GRM5ALDH1A1 | |
| SCHEMBL30740794 | 0.81 | ALDH1A1 (0.40) | GRM5ALDH1A1 | |
| SCHEMBL30740746 | 0.80 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL30745372 | 0.79 | LNPEP (0.39) | GRM5LNPEPGPR119 | |
| SCHEMBL30740829 | 0.77 | LMNA (0.46) | ALDH1A1 | |
| SCHEMBL27477980 | 0.76 | USP30 (0.38) | SCN9AGRM5LNPEPALDH1A1GPR119 | |
| SCHEMBL29826215 | 0.75 | CYP2C9 (0.44) | LNPEPGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |