Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.42 |
| ▸ | CTSB | P07858 | 5/20 | 0.42 |
| ▸ | CTSS | P25774 | 5/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704157 | 0.82 | CTSL (0.47) | CTSLCTSBCTSSCTSKHTR6 | |
| SCHEMBL9984392 | 0.79 | HDAC8 (0.48) | CTSLCTSBCTSSCTSKHTR6 | |
| SCHEMBL27478209 | 0.79 | EHMT2 (0.35) | — | |
| SCHEMBL27478324 | 0.79 | CSNK2A1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL382423 | 0.78 | HDAC8 (0.47) | CTSLCTSBCTSSCTSKHTR6 | |
| SCHEMBL381677 | 0.76 | TRPA1 (0.53) | CTSLCTSBCTSSCTSK | |
| SCHEMBL16465131 | 0.76 | KDM1A (0.43) | NSD2NOS3NOS1NOS2 | |
| SCHEMBL377685 | 0.76 | CTSS (0.48) | CTSLCTSBCTSSCTSK | |
| Hydrochloric Acid SCHEMBL381432 | 0.75 | TRPA1 (0.52) | CTSLCTSBCTSSCTSKHTR6 | |
| Hydrochloric Acid SCHEMBL23302911 | 0.74 | CTSS (0.47) | CTSLCTSBCTSSCTSKHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |