Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27551857 | 0.90 | KMT2A (0.51) | KMT2AFFAR4GAATP53MAOA | |
| SCHEMBL68805 | 0.84 | MAOA (0.52) | KMT2AMAOAMAOBMAPTNPSR1 | |
| SCHEMBL30138896 | 0.84 | MAOA (0.52) | KMT2AMAOAMAOBMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL28311470 | 0.82 | MAOA (0.50) | KMT2AMAOAMAOBMAPTNPSR1 | |
| SCHEMBL27639106 | 0.81 | AHR (0.50) | KMT2AALDH1A1MAOAMAOBATM | |
| SCHEMBL27519942 | 0.81 | MEN1 (0.45) | KMT2AALDH1A1GAAMAOAMAOB | |
| SCHEMBL24910340 | 0.80 | KMT2A (0.51) | KMT2AALDH1A1ALDH2FFAR4HSD17B1 | |
| SCHEMBL12205445 | 0.80 | KMT2A (0.46) | KMT2AALDH1A1ALDH2FFAR4HSD17B1 | |
| SCHEMBL11473460 | 0.79 | ACHE (0.37) | KMT2AALDH1A1ALDH2GAALMNA | |
| SCHEMBL28396444 | 0.79 | MYB (0.44) | KMT2AALDH1A1ALDH2GAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177353-A | Novel quinuclidine derivatives having tricyclic fused hereto ring | YAMANOUCHI PHARMA CO LTD (JP) | 1998-03-25 | — | — | CN | disclosed |