Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501468 | 0.75 | PTGS2 (0.61) | PPARGPPARAFFAR1HDAC2HDAC3 | |
| SCHEMBL1200588 | 0.75 | CA1 (0.53) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL7353438 | 0.74 | SLC1A3 (0.48) | MMP1MMP9MMP13 | |
| SCHEMBL4804285 | 0.74 | CA2 (0.55) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL4201541 | 0.74 | SCD (0.58) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL7058217 | 0.73 | CA2 (0.54) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL27477106 | 0.72 | PPARG (0.52) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL28230363 | 0.72 | CA1 (0.54) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL22206134 | 0.72 | CA1 (0.54) | MMP2CA12CA1CA2CA9 | |
| Acetic Acid SCHEMBL27477993 | 0.71 | KDM4E (0.52) | PPARGPPARAFFAR1HDAC2KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1177821-C | Matrix metalloprotease inhibitors | - | 2004-12-01 | — | — | CN | disclosed |
| CN-1160045-A | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 1997-09-24 | — | — | CN | disclosed |