Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565320 | 0.88 | FFAR1 (0.52) | PTGS2CYP2C9PTGS1LMNAKDM4E | |
| SCHEMBL31261569 | 0.86 | PTGS1 (0.49) | PTGS2CYP2C9PTGS1LMNAKDM4E | |
| SCHEMBL6786159 | 0.80 | FFAR1 (0.54) | PTGS2CYP2C9PTGS1LMNAKDM4E | |
| SCHEMBL6075859 | 0.78 | LTA4H (0.52) | CYP2C9KDM4EALDH1A1HPGDFFAR1 | |
| SCHEMBL917093 | 0.78 | PTGS2 (0.87) | PTGS2CYP2C9PTGS1LMNAAKR1C3 | |
| SCHEMBL24246003 | 0.77 | LTA4H (0.50) | CYP2C9KDM4EALDH1A1HPGDFFAR1 | |
| SCHEMBL27499863 | 0.76 | FFAR1 (0.48) | LMNAKDM4EALDH1A1FFAR1PPARG | |
| SCHEMBL7826539 | 0.76 | PTGS2 (1.00) | PTGS2CYP2C9PTGS1LMNAHPGD | |
| SCHEMBL1211557 | 0.76 | PTGS2 (1.00) | PTGS2CYP2C9PTGS1LMNAHPGD | |
| Acetic Acid SCHEMBL27477993 | 0.76 | KDM4E (0.52) | CYP2C9LMNAKDM4EALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230719-A | Novel 2-[4-(3-methyl-2-thienyl)phenyl]propionic acid and pharmaceutically acceptable salt thereof and method for treating symptoms of inflammation and pain | TOYAMA CHEMICAL CO., LTD. (JP) | 1980-10-28 | — | — | US | disclosed |