Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921580 | 0.77 | NEK2 (0.38) | L3MBTL1ALDH1A1HPGDSIRT6GAA | |
| SCHEMBL9947431 | 0.71 | NEK2 (0.34) | SIRT6GAA | |
| SCHEMBL102874 | 0.71 | SMN1; SMN2 (0.35) | L3MBTL1ALDH1A1HPGDSIRT6 | |
| SCHEMBL7005702 | 0.65 | — | — | |
| SCHEMBL9921596 | 0.64 | GAA (0.38) | ALDH1A1SIRT6GAA | |
| Methane SCHEMBL21847669 | 0.64 | GAA (0.34) | GAAMAPK1 | |
| SCHEMBL86860 | 0.63 | — | — | |
| SCHEMBL13919892 | 0.63 | SIRT6 (0.30) | SIRT6 | |
| SCHEMBL10514616 | 0.61 | — | — | |
| SCHEMBL23267237 | 0.61 | GAA (0.40) | GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1129942-B | Aza spiro-compounds acting on the cholinergic system with muscarinic agonist activity | ISRAEL INST BIOLOG RES | 2011-08-10 | — | — | CN | disclosed |
| CN-1129942-A | Aza spiro-compounds acting on the cholinergic system with muscarinic agonist activity | ISRAEL INST BIOLOG RES (IL) | 1996-08-28 | — | — | CN | disclosed |