Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3751216 | 0.71 | HDAC3 (0.41) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL3404312 | 0.71 | HDAC3 (0.42) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL1007576 | 0.69 | MAPT (0.62) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL5482288 | 0.68 | POLB (0.46) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL5869639 | 0.68 | POLB (0.46) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL29711937 | 0.68 | GPR3 (0.41) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL224931 | 0.68 | GPR3 (0.41) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL7421342 | 0.68 | GPR3 (0.41) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL29196425 | 0.68 | GPR3 (0.41) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL6421466 | 0.67 | GPR3 (0.44) | HDAC3HDAC4HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240605-A | The preparation method of qinghaosu dimer | 中国科学院上海药物研究所 | 2019-09-17 | — | — | CN | claimed |
| CN-110240605-A | The preparation method of qinghaosu dimer | 中国科学院上海药物研究所 | 2019-09-17 | — | — | CN | disclosed |
| CN-107573445-A | Polymer backbone element tags | 富鲁达加拿大公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-101495867-B | Polymer backbone element tag | 富鲁达加拿大公司 | 2017-09-05 | — | — | CN | disclosed |
| CN-101312972-B | Bicyclic cinnamide compound | EISAI R&D MAN CO LTD | 2012-06-20 | — | — | CN | disclosed |
| CN-100590068-C | Method for preparing primary amine carbon nano tube | UNIV TONGJI | 2010-02-17 | — | — | CN | disclosed |
| CN-101448797-A | Heterocyclic type cinnamamide derivative | EISAI R&D MAN CO LTD (JP) | 2009-06-03 | — | — | CN | disclosed |
| CN-100448444-C | Broadspectrum heterocyclic substituted phenyl containing sulfonamide HIV protease inhibitors | TIBOTEC PHARM LTD (IE) | 2009-01-07 | — | — | CN | disclosed |
| CN-101312972-A | Bicyclic cinnamide compound | EISAI R&D MAN CO LTD (JP) | 2008-11-26 | — | — | CN | disclosed |
| CN-101177259-A | Method for preparing primary amine carbon nano tube | UNIV TONGJI (CN) | 2008-05-14 | — | — | CN | disclosed |
| CN-1620292-A | Broadspectrum heterocyclic substituted phenyl containing sulfonamide HIV protease inhibitors | TIBOTEC PHARM LTD (IE) | 2005-05-25 | — | — | CN | disclosed |
| CN-1154647-C | Imidazo 1, 5-naphthyridines and their use in eliciting cytokine biosynthesis | 3M | 2004-06-23 | — | — | CN | disclosed |
| CN-1284957-A | Imidazonaphthyridines and their use in inducing cytokine biosynthesis | MINNESOTA MINING & MFG (US) | 2001-02-21 | — | — | CN | disclosed |