Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 11/20 | 0.49 |
| ▸ | LDHA | P00338 | 2/20 | 0.47 |
| ▸ | TPH1 | P17752 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12134899 | 0.86 | ADORA1 (0.56) | WNT3ANPY5RTPH1BAZ2B | |
| SCHEMBL27483688 | 0.86 | WNT3A (0.45) | WNT3ANPY5RTPH1PRKDCATR | |
| SCHEMBL15214054 | 0.85 | ADORA1 (0.59) | — | |
| SCHEMBL27497340 | 0.84 | HSD17B1 (0.65) | WNT3APRKDCATR | |
| SCHEMBL18132572 | 0.81 | MEN1 (0.57) | WNT3ANPY5RLDHA | |
| SCHEMBL1009480 | 0.81 | CCNE1 (0.45) | WNT3ANPY5RTPH1 | |
| SCHEMBL9951791 | 0.81 | ADORA3 (0.46) | WNT3A | |
| SCHEMBL11521631 | 0.78 | WNT3A (0.45) | WNT3ANPY5RLDHATPH1BAZ2B | |
| SCHEMBL25491310 | 0.77 | ADORA1 (0.58) | WNT3A | |
| SCHEMBL4876684 | 0.76 | DEGS1 (0.58) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100457757-C | Novel spiro compounds | BANYU PHARMA CO LTD (JP) | 2009-02-04 | — | — | CN | disclosed |
| CN-1640877-A | Novel spiro compounds | BANYU PHARMA CO LTD (JP) | 2005-07-20 | — | — | CN | disclosed |
| CN-1202108-C | Spiro compounds, processes and intermediates | BANYU PHARMA CO LTD (JP) | 2005-05-18 | — | — | CN | disclosed |
| CN-1370168-A | Novel spiro compounds | BANYU PHARMA CO LTD (JP) | 2002-09-18 | — | — | CN | disclosed |