SCHEMBL2748167

SCHEMBL2748167

C#CC(F)(F)C(F)(c1ccccc1)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
PTPN1 P18031 2/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA5A P35218 1/20 0.33
CA9 Q16790 1/20 0.33
KCNN4 O15554 2/20 0.32
KIF11 P52732 1/20 0.32
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL951559 0.78 TSHR (0.58) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL8089802 0.72 TSHR (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL8018923 0.72 KCNN4 (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL4259159 0.72 TSHR (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL28845351 0.72 TSHR (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL3084295 0.70 TSHR (0.48) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL3408892 0.70 ALDH1A1 (0.48) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL16886230 0.70 ALDH1A1 (0.48) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL2748164 0.70 TSHR (0.42) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL611603 0.70 TSHR (0.42) TSHRALDH1A1PTPN1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed