Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408892 | 0.89 | ALDH1A1 (0.48) | TSHRALDH1A1KCNN4PTPN1CA1 | |
| SCHEMBL28845351 | 0.86 | TSHR (0.50) | TSHRALDH1A1KCNN4PTPN1CA1 | |
| SCHEMBL8018923 | 0.86 | KCNN4 (0.50) | TSHRALDH1A1KCNN4PTPN1CA1 | |
| SCHEMBL8089802 | 0.86 | TSHR (0.50) | TSHRALDH1A1KCNN4PTPN1CA1 | |
| SCHEMBL16886230 | 0.84 | ALDH1A1 (0.48) | TSHRALDH1A1KCNN4PTPN1CA1 | |
| SCHEMBL3084295 | 0.84 | TSHR (0.48) | TSHRALDH1A1KCNN4PTPN1CA1 | |
| SCHEMBL28819791 | 0.84 | KIF11 (0.65) | TSHRALDH1A1PTPN1KIF11MAPK1 | |
| SCHEMBL497772 | 0.83 | ESR1 (0.41) | TSHRALDH1A1KIF11PGK1PGK2 | |
| Water SCHEMBL29107395 | 0.82 | ALDH1A1 (0.46) | TSHRALDH1A1KCNN4PTPN1CA1 | |
| SCHEMBL24961819 | 0.79 | PGK1 (0.44) | TSHRALDH1A1KCNN4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169955-B2 | Perfluoroisopropylbenzene derivative | NIHON NOHYAKU CO., LTD. (JP) | 2007-01-30 | — | — | US | claimed |
| EP-1619175-A1 | Process for the preparation of fluorinated alkyl-substituted aromatic compounds | Solvay Fluor GmbH (DE) | 2006-01-25 | — | — | EP | claimed |
| US-20050113567-A1 | Perfluoroisopropylbenzene derivative | NIHON NOHYAKU CO., LTD. (JP) | 2005-05-26 | — | — | US | claimed |
| US-20030187233-A1 | PERFLUOROISOPROPYBENZENE DERIVATIVE | NIHON NOHYAKU CO., LTD. (JP) | 2003-10-02 | — | — | US | claimed |
| EP-1253128-A1 | PERFLUOROISOPROPYLBENZENE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2002-10-30 | — | — | EP | claimed |
| EP-3911658-B1 | METHOD FOR PREPARATION OF FLUORO ALKYLATED COMPOUNDS BY HOMOGENEOUS NI CATALYSIS | ARXADA AG (CH) | 2023-01-11 | — | — | EP | disclosed |
| US-11530175-B2 | Method for preparation of fluoro alkylated compounds by homogeneous Ni catalysis | ARXADA AG (CH) | 2022-12-20 | — | — | US | disclosed |
| CN-110776406-B | Novel Friedel-Crafts reaction method and catalyst thereof | 福建永晶科技股份有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-11465958-B2 | Process for Friedel-Crafts reaction, and catalyst therefore | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2022-10-11 | — | — | US | disclosed |
| US-20220221619-A1 | MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME | OTI LUMIONICS INC. (CA) | 2022-07-14 | — | — | US | disclosed |
| US-20220041530-A1 | Method for Preparation of Fluoro Alkylated Compounds by Homogeneous NI Catalysis | LONZA LTD (CH) | 2022-02-10 | — | — | US | disclosed |
| CN-107722148-B | Solid polyaluminoxane composition, catalyst for olefin polymerization, and method for producing olefin polymer | 三井化学株式会社 | 2021-06-08 | — | — | CN | disclosed |
| EP-1253128-A1 | PERFLUOROISOPROPYLBENZENE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2002-10-30 | — | — | EP | disclosed |
| JP-2001288129-A | PERFLUOROISOPROPYLBENZENE DERIVATIVE | NIPPON NOHYAKU CO LTD | 2001-10-16 | — | — | JP | disclosed |
| WO-2001056962-A1 | PERFLUOROISOPROPYLBENZENE DERIVATIVES | NIHON NOHYAKU CO., LTD. (JP) | 2001-08-09 | — | — | WO | disclosed |
| EP-0082252-B1 | PROCESS FOR PRODUCING FLUORINE-CONTAINING ORGANIC COMPOUND | Daikin Kogyo Co., Ltd. (JP) | 1985-08-21 | — | — | EP | disclosed |
| US-4484993-A | ULTRASONIC ENERGY | DAIKIN KOGYO CO., LTD. (JP) | 1984-11-27 | — | — | US | disclosed |
| EP-0082252-A1 | Process for producing fluorine-containing organic compound | Daikin Kogyo Co., Ltd. (JP) | 1983-06-29 | — | — | EP | disclosed |
| US-4096180-A | Fluorodehydroxylation of serine | MERCK & CO., INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4001406-A | BENZENEDISULFONAMIDES AS ANTHELMINTIC AGENTS | MERCK & CO., INC. (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11465958-B2 | Process for Friedel-Crafts reaction, and catalyst therefore | HNF4A, TFEB, HACL2 | TSHR 2377/4885ALDH1A1 497/4885KCNN4 2997/4885 |
| US-20220041530-A1 | Method for Preparation of Fluoro Alkylated Compounds by Homogeneous NI Catalysis | ABL1, AFF2, NAF1 | TSHR 1725/4885ALDH1A1 1150/4885KCNN4 681/4885 |
| US-20030187233-A1 | PERFLUOROISOPROPYBENZENE DERIVATIVE | AFF1, CBR1, RER1 | TSHR 232/4885ALDH1A1 1079/4885KCNN4 1028/4885 |
| US-11530175-B2 | Method for preparation of fluoro alkylated compounds by homogeneous Ni catalysis | ABL1, AFF2, NAF1 | TSHR 1725/4885ALDH1A1 1150/4885KCNN4 681/4885 |
| US-20050113567-A1 | Perfluoroisopropylbenzene derivative | FFAR3, CBR3, HCAR3 | TSHR 60/4885ALDH1A1 2953/4885KCNN4 829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.