SCHEMBL8089802

SCHEMBL8089802

FC(F)(F)C(F)(c1ccccc1)C(F)(F)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ALDH1A1 P00352 1/20 0.50
PTPN1 P18031 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
KCNN4 O15554 3/20 0.38
KIF11 P52732 2/20 0.37
MAPK1 P28482 1/20 0.33
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
PTPN5 P54829 1/20 0.31
TRPV6 Q9H1D0 1/20 0.31
CES2 O00748 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL951559 0.86 TSHR (0.58) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL9779084 0.82 SRD5A2 (0.50) TSHRPTPN1KIF11CES2
SCHEMBL16477711 0.81 TSHR (0.52) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL146900 0.80 TSHR (0.58) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL17288747 0.80 TSHR (0.58) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL9723026 0.80 ALDH1A1 (0.65) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL8018923 0.79 KCNN4 (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL28845351 0.79 TSHR (0.50) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL3408892 0.77 ALDH1A1 (0.48) TSHRALDH1A1PTPN1CA1CA2
SCHEMBL16886230 0.77 ALDH1A1 (0.48) TSHRALDH1A1PTPN1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111019346-B Flame-retardant high-heat-resistance resin composition, copper-clad plate and preparation method thereof 艾蒙特成都新材料科技有限公司 2022-08-12 CN claimed
US-10071345-B2 Polybenzimidazole hollow fiber membranes and method for making an asymmetric hollow fiber membrane LOS ALAMOS NATIONAL SECURITY, LLC (US) 2018-09-11 US claimed
CN-108350145-A Cyanate dual cure resin for increasing material manufacturing 卡本有限公司 2018-07-31 CN claimed
US-9663617-B2 Fluorine-containing modified bismaleimide resin NAN YA PLASTICS CORPORATION (TW) 2017-05-30 US claimed
US-20160375410-A1 POLYBENZIMIDAZOLE HOLLOW FIBER MEMBRANES AND METHOD FOR MAKING AN ASYMMETRIC HOLLOW FIBER MEMBRANE LOS ALAMOS NATIONAL SECURITY, LLC (US) 2016-12-29 US claimed
US-20160168330-A1 FLUORINE-CONTAINING MODIFIED BISMALEIMIDE RESIN NAN YA PLASTICS CORPORATION (TW) 2016-06-16 US claimed
EP-0560084-A2 Mechanically enhanced, high impact strength triazine resins, and method of preparing same International Business Machines Corporation (US) 1993-09-15 EP claimed
EP-0192766-B1 ETHYNYLPHENOXY AND ETHYNYLTHIOPHENOXY DERIVATIVES OF DIPHENYLHEXAFLUOROPROPANE Hughes Aircraft Company (US) 1988-09-21 EP claimed
JP-6254367-A None JP disclosed
US-12636618-B1 Asymmetric carbon molecular sieve hollow fiber membranes TRIAD NATIONAL SECURITY, LLC (US) 2026-05-26 US disclosed
EP-4692938-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, DRY FILM, CURED PRODUCT, AND ELECTRONIC COMPONENT TAIYO HOLDINGS CO., LTD. (JP) 2026-02-11 EP disclosed
US-20250277077-A1 RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND CURED PRODUCT OF RESIN COMPOSITION RESONAC CORPORATION (JP) 2025-09-04 US disclosed
US-20250101181-A1 RESIN COMPOSITION AND PRODUCTION METHOD THEREFOR, AND CURED PRODUCT OF RESIN COMPOSITION RESONAC CORPORATION (JP) 2025-03-27 US disclosed
CN-118621617-B Preparation method of waterproof paper attached with waterproof and oil-proof film 中山泰星纸袋制品有限公司 2025-03-14 CN disclosed
US-4866156-A Poly(arylether) or poly(arylthioether) from 2,2-bis(fluorophenyl)-hexafluoropropane HUGHES AIRCRAFT COPMANY (US) 1989-09-12 US disclosed
US-4827054-A Method for synthesizing 2,2-bis(4-fluorophenyl)-hexafluoropropane and method for using same to synthesize poly(arylethers) and poly (arylthioethers) HUGHES AIRCRAFT COMPANY (US) 1989-05-02 US disclosed
US-4814472-A Diethynylated diphenyl hexafluoropropanes HUGHES AIRCRAFT COMPANY (US) 1989-03-21 US disclosed
US-4814472-A Diethynylated diphenyl hexafluoropropanes HUGHES AIRCRAFT COMPANY (US) 1989-03-21 US disclosed
EP-0192766-A1 ETHYNYLPHENOXY AND ETHYNYLTHIOPHENOXY DERIVATIVES OF DIPHENYLHEXAFLUOROPROPANE. HUGHES AIRCRAFT CO (US) 1986-09-03 EP disclosed
WO-1986001504-A1 ETHYNYLPHENOXY AND ETHYNYLTHIOPHENOXY DERIVATIVES OF DIPHENYLHEXAFLUOROPROPANE HUGHES AIRCRAFT COMPANY (US) 1986-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636618-B1 Asymmetric carbon molecular sieve hollow fiber membranes PHB2, PHB1, RICTOR TSHR 4620/4885ALDH1A1 4525/4885PTPN1 4878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.