Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27367023 | 0.93 | POLB (0.41) | POLBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5515342 | 0.90 | SLC5A1 (0.45) | POLBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL27369607 | 0.88 | MAPT (0.39) | POLBMAPTSMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL27482671 | 0.86 | POLB (0.42) | POLBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5516696 | 0.85 | SLC5A1 (0.44) | POLBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8069350 | 0.85 | SLC5A1 (0.44) | POLBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7828627 | 0.85 | SLC5A1 (0.44) | POLBMAPTSMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL8067119 | 0.83 | SLC5A1 (0.43) | POLBMAPTSMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL7827659 | 0.81 | SLC5A1 (0.43) | POLBMAPTSMN1; SMN2ALOX15L3MBTL1 | |
| SCHEMBL5519562 | 0.80 | LMNA (0.47) | POLBMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100387580-C | Tricyclic triazolobenzazepine * derivatives, process for preparing the same, and antiallergic agent | MEIJI SEIKA KAISHA (JP) | 2008-05-14 | — | — | CN | disclosed |
| CN-1312135-C | Tricyclic triazolobenzazepine * derivatives, process for preparing the same, and antiallergic agent | MEIJI SEIKA KAISHA (JP) | 2007-04-25 | — | — | CN | disclosed |
| CN-1781913-A | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agent | MEIJI SEIKA KAISHA (JP) | 2006-06-07 | — | — | CN | disclosed |
| CN-1523019-A | Tricyclic triazolobenzazepine * derivatives, process for preparing the same, and antiallergic agent | �����Ƹ���ʽ���� | 2004-08-25 | — | — | CN | disclosed |
| CN-1155599-C | Tricyclic triazolobenzazepine * derivatives, process for preparing the same, and antiallergic agent | �����Ƹ���ʽ���� | 2004-06-30 | — | — | CN | disclosed |
| CN-1278262-A | Tricyclic triazolobenzazepine * derivatives, process for preparing the same, and antiallergic agent | MEIJI SEIKA KAISHA (JP) | 2000-12-27 | — | — | CN | disclosed |