Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982954 | 0.79 | ALDH1A1 (0.41) | PTGDR2ALOX15ALDH1A1LMNATP53 | |
| SCHEMBL1542948 | 0.79 | PTGDR2 (0.56) | PTGDR2ALOX15USP2ALPLMAPK1 | |
| SCHEMBL29426974 | 0.79 | PTGDR2 (0.56) | PTGDR2ALOX15USP2ALPLMAPK1 | |
| SCHEMBL9860765 | 0.78 | LMNA (0.32) | PTGDR2ALOX15ALDH1A1LMNATP53 | |
| SCHEMBL1826724 | 0.75 | PTGDR2 (0.33) | PTGDR2ALOX15ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13748304 | 0.74 | PTGDR2 (0.64) | PTGDR2ALOX15USP2ALPLMAPK1 | |
| SCHEMBL7587512 | 0.74 | PTGDR2 (0.51) | PTGDR2ALOX15USP2ALPLMAPK1 | |
| SCHEMBL8515160 | 0.74 | PTGDR2 (0.51) | PTGDR2ALOX15USP2ALPLMAPK1 | |
| SCHEMBL2415131 | 0.74 | S1PR4 (0.42) | PTGDR2ALOX15USP2ALPLMAPK1 | |
| SCHEMBL25354930 | 0.73 | MAPK1 (0.39) | PTGDR2ALOX15MAPK1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251408-B1 | NOVEL ANTI-INFLAMMATORY AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR REDUCING INFLAMMATION | THE PROCTER & GAMBLE COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| EP-0251408-A1 | Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation | THE PROCTER & GAMBLE COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |