Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17311030 | 0.81 | PTGDR2 (0.61) | PTGDR2USP2ALPLALOX15MEN1 | |
| SCHEMBL2599760 | 0.80 | ALDH1A1 (0.49) | ALOX15TP53MDM2MEN1KMT2A | |
| SCHEMBL671015 | 0.78 | KMT2A (0.54) | TP53MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL15253372 | 0.78 | NPSR1 (0.47) | ALOX15TP53MEN1HTTKMT2A | |
| SCHEMBL13748304 | 0.77 | PTGDR2 (0.64) | PTGDR2USP2ALPLALOX15MEN1 | |
| SCHEMBL12478128 | 0.77 | PTGDR2 (1.00) | PTGDR2USP2ALPLALOX15MEN1 | |
| SCHEMBL27481998 | 0.76 | PTGDR2 (0.51) | PTGDR2USP2ALPLALOX15TP53 | |
| SCHEMBL3584577 | 0.76 | PTGES (0.46) | PTGDR2TRPA1MTNR1APTGESHPGD | |
| SCHEMBL4448846 | 0.76 | PTGDR2 (0.64) | PTGDR2TP53MDM2MEN1KMT2A | |
| SCHEMBL7140056 | 0.76 | PTGDR2 (0.38) | PTGDR2ALOX15TP53MDM2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907646-B1 | DIHYDROBENZOPYRAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIV VANDERBILT (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6110960-A | FOR TREATING ARTHRITIS AND AS ANALGESIC | THE PROCTER & GAMBLE COMPANY (US) | 2000-08-29 | — | — | US | disclosed |