Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL280282 | 0.83 | EGLN1 (0.57) | GCGRMAOB | |
| SCHEMBL14055876 | 0.83 | KDM4E (0.54) | GCGRMAOBHIF1ALMNA | |
| SCHEMBL19289588 | 0.82 | TP53 (0.54) | MAOBHIF1A | |
| SCHEMBL27699630 | 0.80 | HIF1A (0.72) | HIF1A | |
| SCHEMBL1976949 | 0.78 | CNR1 (0.47) | MAOBLMNA | |
| SCHEMBL27480913 | 0.78 | P4HTM (0.64) | GCGRHIF1A | |
| SCHEMBL10186381 | 0.77 | CYP1A2 (0.58) | MAOB | |
| SCHEMBL2142248 | 0.76 | EGFR (0.62) | HIF1A | |
| SCHEMBL8282027 | 0.75 | P2RX7 (0.52) | MAOBHIF1A | |
| SCHEMBL3188696 | 0.75 | KMT2A (0.71) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1182119-C | Astalosin like anti-cancer compound and making process and usage thereof | 怡发科技股份有限公司 | 2004-12-29 | — | — | CN | disclosed |