Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699630 | 0.85 | HIF1A (0.72) | EGFRLCKHIF1ASMN1; SMN2 | |
| SCHEMBL13210567 | 0.84 | L3MBTL1 (0.76) | EGFRMMP13HPGDGLAPRKAA2 | |
| SCHEMBL11633297 | 0.83 | MMP13 (0.59) | EGFRMMP13LCKHPGDGLA | |
| SCHEMBL1019074 | 0.83 | L3MBTL1 (0.65) | EGFRMMP13HPGDGLAPRKAA2 | |
| SCHEMBL12266355 | 0.83 | MMP13 (0.59) | EGFRMMP13LCKHPGDGLA | |
| SCHEMBL9967496 | 0.80 | MMP13 (0.55) | EGFRMMP13LCKHPGDGLA | |
| SCHEMBL3083971 | 0.79 | HTT (0.75) | MMP13HPGDHPGDSHTTALDH1A1 | |
| SCHEMBL29733373 | 0.79 | HTT (0.75) | MMP13HPGDHPGDSHTTALDH1A1 | |
| SCHEMBL1018162 | 0.79 | L3MBTL1 (0.60) | EGFRMMP13HPGDGLAPRKAA2 | |
| Hydrochloric Acid SCHEMBL27924615 | 0.78 | HTT (0.73) | MMP13HPGDHPGDSHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148407-B2 | Compounds derived from 5-thioxylose and their use in therapeutics | LABORATORIES FOURNIER S.A. (FR) | 2012-04-03 | — | — | US | disclosed |
| US-20080293768-A1 | Novel Compounds Derived From 5-Thioxylose And Their Use In Therapeutics | INVENTIVA (FR) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293768-A1 | Novel Compounds Derived From 5-Thioxylose And Their Use In Therapeutics | TPMT, STS, TBXAS1 | EGFR 4467/4885MMP13 2117/4885LCK 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.