Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.72 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703654 | 0.85 | HIF1A (0.72) | HIF1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28608835 | 0.85 | HIF1A (0.85) | HIF1ARAB9ANPC1EGFRLCK | |
| SCHEMBL2142248 | 0.85 | EGFR (0.62) | HIF1AEGFRLCKSMN1; SMN2 | |
| SCHEMBL28344799 | 0.84 | HIF1A (1.00) | HIF1ARAB9ANPC1EGFRLCK | |
| SCHEMBL30131466 | 0.80 | KMT2A (0.69) | HIF1ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL27482073 | 0.80 | GCGR (0.50) | HIF1A | |
| SCHEMBL7704092 | 0.80 | KMT2A (0.69) | HIF1ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL19289588 | 0.78 | TP53 (0.54) | HIF1ARAB9ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL19508074 | 0.78 | NPC1 (0.76) | HIF1ARAB9ANPC1EGFRLCK | |
| SCHEMBL28607757 | 0.77 | HIF1A (1.00) | HIF1ARAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146817-B | Novel compounds derived from 5-thioxylose and therapeutic use thereof | FOURNIER LAB SA | 2011-08-17 | — | — | CN | disclosed |
| CN-101146817-A | Novel compounds derived from 5-thioxylose and therapeutic use thereof | FOURNIER LAB SA (FR) | 2008-03-19 | — | — | CN | disclosed |