Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ACP3 | P15309 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27346979 | 0.84 | CYP2C19 (0.47) | CYP2C9CYP2C19HPGDHTTCASP1 | |
| SCHEMBL24258027 | 0.81 | CYP2C19 (0.46) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL656946 | 0.80 | HPGD (0.62) | CYP2C9CYP2C19HPGDHTTCASP1 | |
| SCHEMBL10354936 | 0.78 | HPGD (0.60) | CYP2C9CYP2C19HPGDHTTCASP1 | |
| SCHEMBL28782552 | 0.78 | ALDH1A1 (0.46) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL614835 | 0.78 | CYP2C9 (0.46) | CYP2C9CYP2C19HPGDHTTALDH1A1 | |
| SCHEMBL11846737 | 0.78 | MMP12 (0.39) | CYP2C9CYP2C19HPGDHTTCASP1 | |
| SCHEMBL1520324 | 0.77 | HPGD (0.59) | CYP2C9CYP2C19HPGDHTTCASP1 | |
| SCHEMBL6743921 | 0.77 | CYP2C9 (0.59) | CYP2C9CYP2C19HPGDHTTCASP1 | |
| SCHEMBL5720984 | 0.77 | HPGD (0.59) | CYP2C9CYP2C19HPGDHTTCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1188407-C | Imidazole derivatives with inhabiting activity to transterasa and preparing method thereof | LG CHEMICAL LTD (KR) | 2005-02-09 | — | — | CN | disclosed |
| CN-1279680-A | Imidazole derivatives having farnesyl transferase inhibitory activity and process for producing the same | LG CHEMICAL LTD (KR) | 2001-01-10 | — | — | CN | disclosed |