Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | CEL | P19835 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | PPM1D | O15297 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28175591 | 0.98 | KDM5B (0.40) | KDM5BKDM5ARARBCELPTGER4 | |
| SCHEMBL28850083 | 0.79 | NOTUM (0.37) | CELPTGER4KDM4CMCL1KDM4E | |
| SCHEMBL27417962 | 0.77 | GABRP (0.41) | — | |
| SCHEMBL28127936 | 0.75 | METAP2 (0.40) | PTGER4 | |
| SCHEMBL27385522 | 0.74 | METAP2 (0.36) | KDM4EHPGD | |
| SCHEMBL27968107 | 0.74 | CYP1A2 (0.37) | KDM4EHPGD | |
| SCHEMBL28126408 | 0.74 | CYP1A2 (0.37) | KDM4EHPGD | |
| SCHEMBL27287111 | 0.74 | GABRP (0.38) | KDM4E | |
| SCHEMBL27536275 | 0.74 | DCLRE1B (0.45) | — | |
| SCHEMBL27535391 | 0.74 | CYP1A2 (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1244575-C | Sulfonylalkylamido hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1183767-A | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 1998-06-03 | — | — | CN | disclosed |