SCHEMBL274839

SCHEMBL274839

c1ccc(Nn2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 5/20 0.70
KDM4E B2RXH2 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
GPR3 P46089 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 1/20 0.41
DNM1 Q05193 1/20 0.41
CYP19A1 P11511 1/20 0.40
TDP1 Q9NUW8 4/20 0.38
MEN1 O00255 3/20 0.38
GAA P10253 3/20 0.38
MAPT P10636 3/20 0.38
KMT2A Q03164 3/20 0.38
GLA P06280 1/20 0.38
RECQL P46063 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 2/20 0.38
CTSD P07339 1/20 0.38
MAPK1 P28482 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30258185 0.87 SLC6A2 (0.61) SLC6A2KDM4EL3MBTL1ATMGPR3
SCHEMBL9663500 0.83 SLC6A2 (1.00) SLC6A2GPR3CTSD
SCHEMBL21376874 0.78 SLC6A2 (0.47) SLC6A2L3MBTL1ALDH1A1HSD17B10FABP4
SCHEMBL29065263 0.78 SLC6A2 (0.51) SLC6A2KDM4ETDP1MEN1GAA
Fumaric Acid SCHEMBL9665744 0.75 SLC6A2 (1.00) SLC6A2KDM4EALDH1A1POLBLMNA
SCHEMBL28984617 0.73 SLC6A2 (0.42) SLC6A2L3MBTL1MAPTALDH1A1RAB9A
SCHEMBL12439957 0.70 GPR3 (0.52) SLC6A2KDM4EL3MBTL1ATMGPR3
SCHEMBL9663505 0.69 SLC6A2 (0.55) SLC6A2KDM4EATMCYP1A2MEN1
SCHEMBL11539692 0.68 CYP3A4 (0.45) SLC6A2KDM4EL3MBTL1CYP1A2CYP2C19
SCHEMBL19259501 0.68 SLC6A2 (0.50) SLC6A2KDM4EL3MBTL1ATMCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111484443-B Anilinocarbazole-based hole transport material and application thereof 太原理工大学 2023-04-07 CN claimed
CN-111484443-A Anilinocarbazole-based hole transport material and application thereof 太原理工大学 2020-08-04 CN claimed
CN-111484443-B Anilinocarbazole-based hole transport material and application thereof 太原理工大学 2023-04-07 CN disclosed
CN-114695767-A Organic electroluminescent device and polycyclic compound for organic electroluminescent device 三星显示有限公司 2022-07-01 CN disclosed
CN-111484443-A Anilinocarbazole-based hole transport material and application thereof 太原理工大学 2020-08-04 CN disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-14 US disclosed
US-8704215-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-04-22 US disclosed
US-20120168741-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-07-05 US disclosed
US-8134148-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-13 US disclosed
US-20100301322-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-12-02 US disclosed
US-7732619-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-5863936-A HETEROCYCLIC ENZYME INHIBITORS AS ANTICANCER AGENTS GERON CORPORATION (US) 1999-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 SLC6A2 2657/4885KDM4E 3249/4885L3MBTL1 2886/4885
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 SLC6A2 2657/4885KDM4E 3249/4885L3MBTL1 2886/4885
US-20120168741-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 SLC6A2 2657/4885KDM4E 3249/4885L3MBTL1 2886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.