Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | FABP4 | P15090 | 4/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504871 | 0.82 | CYP3A4 (0.59) | SLC6A2KDM4ELMNAHTTHDAC6 | |
| SCHEMBL31241488 | 0.81 | POLB (0.55) | SLC6A2KDM4EFABP4FABP5POLB | |
| SCHEMBL8836561 | 0.80 | ALDH1A1 (0.42) | SLC6A2KDM4EFABP4FABP5POLB | |
| SCHEMBL30766244 | 0.77 | LIPE (0.47) | SLC6A2KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL19272150 | 0.77 | LIPE (0.47) | SLC6A2KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL28754715 | 0.75 | POLB (0.48) | SLC6A2KDM4EFABP4FABP5POLB | |
| SCHEMBL19272298 | 0.75 | KDM4E (0.42) | SLC6A2KDM4EFABP4FABP5POLB | |
| SCHEMBL31241484 | 0.74 | CYP3A4 (0.54) | KDM4EPOLBALDH1A1LMNAMAPT | |
| SCHEMBL31241487 | 0.74 | CYP3A4 (0.54) | KDM4EPOLBALDH1A1LMNAMAPT | |
| SCHEMBL31241486 | 0.74 | CYP3A4 (0.54) | KDM4EPOLBALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858922-B2 | Sulfonylureas and related compounds and use of same | THE UNIVERSITY OF QUEENSLAND (AU) | 2024-01-02 | — | — | US | disclosed |
| US-20200299284-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | INFLAZOME LIMITED (IE) | 2020-09-24 | — | — | US | disclosed |
| EP-3416948-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University Of Queensland (AU) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017140778-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858922-B2 | Sulfonylureas and related compounds and use of same | NLRP3, NOD1, PYCARD | SLC6A2 2259/4885KDM4E 2827/4885FABP4 1843/4885 |
| US-20200299284-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | NLRP3, NOD1, PYCARD | SLC6A2 2259/4885KDM4E 2827/4885FABP4 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.