Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29894014 | 0.84 | KMT2A (0.35) | KMT2AHIF1ASMN1; SMN2ESR1RECQL | |
| SCHEMBL312147 | 0.75 | KMT2A (0.76) | KMT2AHIF1ASMN1; SMN2ESR1RECQL | |
| SCHEMBL20665985 | 0.74 | ELANE (0.50) | ELANEMAPTLMNAALOX15GAA | |
| SCHEMBL26698294 | 0.74 | ACHE (0.46) | KMT2AHIF1ASMN1; SMN2ESR1RECQL | |
| SCHEMBL11445596 | 0.73 | KMT2A (0.73) | KMT2AHIF1ASMN1; SMN2ESR1RECQL | |
| SCHEMBL28011750 | 0.72 | ELANE (0.70) | KMT2AHIF1ASMN1; SMN2ESR1RECQL | |
| SCHEMBL45119 | 0.70 | ELANE (0.72) | KMT2AHIF1ASMN1; SMN2ESR1RECQL | |
| SCHEMBL6282777 | 0.70 | KMT2A (0.68) | KMT2AHIF1ASMN1; SMN2ESR1RECQL | |
| SCHEMBL9171166 | 0.70 | KMT2A (0.68) | KMT2AHIF1ASMN1; SMN2ESR1RECQL | |
| SCHEMBL9799566 | 0.70 | ELANE (0.72) | KMT2AHIF1ASMN1; SMN2ESR1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201740-C | Medicine for treating intermittent claudication containing pyrroloazepine * compound | DAIICHI SUNTORY LTD (JP) | 2005-05-18 | — | — | CN | disclosed |
| CN-1297351-A | Medicine for treating intermittent claudication containing pyrroloazepine * compound | SUNTORY LTD (JP) | 2001-05-30 | — | — | CN | disclosed |