Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14856800 | 0.81 | HAO1 (0.38) | KMT2AKDM4EHPGDMAPTPIK3C3 | |
| SCHEMBL26698236 | 0.81 | LMNA (0.46) | ACHEKMT2AALDH1A1KDM4EGAA | |
| SCHEMBL27741946 | 0.76 | MTNR1A (0.46) | ACHEHIF1AKMT2AESR1RECQL | |
| SCHEMBL27762475 | 0.76 | MTNR1A (0.47) | ACHEHIF1AKMT2AESR1RECQL | |
| SCHEMBL27484101 | 0.74 | KMT2A (0.49) | ACHEHIF1AKMT2AESR1RECQL | |
| SCHEMBL10782553 | 0.72 | ACHE (0.71) | ACHEHIF1AKMT2AESR1RECQL | |
| SCHEMBL4810016 | 0.72 | TUBB4A (0.47) | RECQLSMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL31598867 | 0.72 | TUBB4A (0.37) | KMT2AKDM4EHPGDMAPTPIK3C3 | |
| SCHEMBL312147 | 0.71 | KMT2A (0.76) | ACHEHIF1AKMT2AESR1RECQL | |
| SCHEMBL15721894 | 0.71 | L3MBTL1 (0.47) | KMT2AALDH1A1GAAUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |