Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174643 | 0.94 | MMP8 (0.56) | MMP8L3MBTL1CA12CA1CA2 | |
| SCHEMBL27499665 | 0.91 | MMP8 (0.50) | MMP8L3MBTL1CA12CA1CA2 | |
| SCHEMBL27520010 | 0.90 | MMP8 (0.46) | MMP8L3MBTL1SMN1; SMN2 | |
| SCHEMBL27485655 | 0.90 | MMP8 (0.55) | MMP8L3MBTL1CA12CA1CA2 | |
| SCHEMBL27484988 | 0.90 | L3MBTL1 (0.49) | MMP8L3MBTL1MEN1NPC1KMT2A | |
| SCHEMBL27499980 | 0.88 | TSHR (0.46) | MMP8L3MBTL1NPC1TSHRSMN1; SMN2 | |
| SCHEMBL27500265 | 0.87 | NPC1 (0.45) | MMP8L3MBTL1MEN1NPC1KMT2A | |
| SCHEMBL27485279 | 0.87 | ALDH1A1 (0.45) | MMP8L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL27486010 | 0.87 | TSHR (0.47) | MMP8L3MBTL1NPC1TSHRSMN1; SMN2 | |
| SCHEMBL7183564 | 0.86 | MMP8 (0.54) | MMP8L3MBTL1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |