Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27485658 | 0.91 | RAB9A (0.41) | MAPTLMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL27484933 | 0.90 | MAPT (0.42) | MAPTLMNASMN1; SMN2HTTHPGD | |
| SCHEMBL27500272 | 0.87 | LMNA (0.45) | MAPTLMNASMN1; SMN2HTTHPGD | |
| SCHEMBL27500969 | 0.85 | HPGD (0.42) | MAPTLMNASMN1; SMN2HTTHPGD | |
| SCHEMBL27500281 | 0.81 | MAPT (0.43) | MAPTLMNASMN1; SMN2HTTHPGD | |
| SCHEMBL27194792 | 0.79 | BCL2L1 (0.40) | MAPTLMNASMN1; SMN2HTTHPGD | |
| SCHEMBL27561239 | 0.77 | MAPT (0.45) | MAPTLMNASMN1; SMN2HTTHPGD | |
| SCHEMBL2288468 | 0.75 | MAPT (0.54) | MAPTLMNASMN1; SMN2HTTHPGD | |
| SCHEMBL27498758 | 0.75 | MAPT (0.42) | MAPTLMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL7178047 | 0.74 | MAPT (0.38) | MAPTLMNASMN1; SMN2HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |