Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484933 | 0.92 | MAPT (0.42) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL27485658 | 0.89 | RAB9A (0.41) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL27561239 | 0.87 | MAPT (0.45) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL27484262 | 0.81 | MAPT (0.39) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL27498758 | 0.81 | MAPT (0.42) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL27500272 | 0.81 | LMNA (0.45) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL27500969 | 0.74 | HPGD (0.42) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL27483932 | 0.73 | CYP2C9 (0.33) | LMNAHPGDKDM4EHSD17B10CYP3A4 | |
| SCHEMBL7188418 | 0.72 | MAPT (0.43) | MAPTLMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL3894224 | 0.71 | MAPT (0.59) | MAPTLMNAHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1200943-C | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2005-05-11 | — | — | CN | disclosed |
| CN-1308081-A | Organometallic acyl-aryl phosphine | CIBA SC HOLDING AG (CH) | 2001-08-15 | — | — | CN | disclosed |