Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL27464625 | 0.96 | CYP11B1 (0.32) | CYP11B1CYP11B2HTR2ATP53 | |
| Bromide SCHEMBL27948604 | 0.96 | HTR2A (0.35) | CYP11B1CYP11B2HTR2ATP53 | |
| Fluoride Ion SCHEMBL27933059 | 0.96 | CYP11B1 (0.32) | CYP11B1CYP11B2HTR2ATP53 | |
| SCHEMBL27372929 | 0.82 | CYP11B1 (0.33) | CYP11B1CYP11B2HTR2ATP53 | |
| Fluoride Ion SCHEMBL27933166 | 0.81 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| Iodide SCHEMBL27933217 | 0.81 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7195488 | 0.78 | CYP11B1 (0.37) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL29651804 | 0.78 | CYP11B1 (0.37) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL7937296 | 0.78 | CYP11B1 (0.34) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL27387860 | 0.78 | CYP11B1 (0.34) | CYP11B1CYP11B2HTR2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103443171-B | Polyethylene film | 伊奎斯塔化学有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-103509060-B | Metallocene compound, the carbon monoxide-olefin polymeric comprising metallocene compound and the olefine polymerizing process of use metallocene compound | 大林产业株式会社 | 2016-08-10 | — | — | CN | disclosed |
| CN-101652178-B | Iron complexes and their use in polymerization processes | BASELL POLYOLEFINE GMBH | 2014-08-27 | — | — | CN | disclosed |
| CN-103946330-A | Systems, methods and compositions for production of tie-layer adhesives | EQUISTAR CHEM LP | 2014-07-23 | — | — | CN | disclosed |
| CN-103509060-A | Metallocene compound, catalyst composite containing metallocene compound and olefin polymerization method using metallocene compound | DAELIM IND CO LTD | 2014-01-15 | — | — | CN | disclosed |
| CN-103443171-A | Polyethylene films | EQUISTAR CHEM LP | 2013-12-11 | — | — | CN | disclosed |
| CN-101652178-A | Iron complexes and their use in polymerization processes | BASELL POLYOLEFINE GMBH DE | 2010-02-17 | — | — | CN | disclosed |
| CN-1274359-A | Mu-oxometallocene complex compound, and olefin polymerization catalyst and polymerization method using same | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1202186-A | Propene/but-1-ene copolymer | BASF AG (DE) | 1998-12-16 | — | — | CN | disclosed |
| CN-1201468-A | Process for producing propene-1-butene copolymers | BASF AG (DE) | 1998-12-09 | — | — | CN | disclosed |