Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27484580 | 0.78 | CYP11B1 (0.35) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL27387860 | 0.77 | CYP11B1 (0.34) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL27461592 | 0.77 | CYP11B1 (0.34) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL29651804 | 0.77 | CYP11B1 (0.37) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL7195488 | 0.77 | CYP11B1 (0.37) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| SCHEMBL27372929 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2HTR2A | |
| SCHEMBL5859366 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2HTR2A | |
| SCHEMBL6344924 | 0.76 | DRD2 (0.38) | CYP11B1CYP11B2HTR2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL2519660 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL29612292 | 0.76 | CYP11B1 (0.33) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509060-B | Metallocene compound, the carbon monoxide-olefin polymeric comprising metallocene compound and the olefine polymerizing process of use metallocene compound | 大林产业株式会社 | 2016-08-10 | — | — | CN | disclosed |
| US-6232414-B1 | USING ORGANOMETALLIC COORDINATION CATALYST | PHILLIPS PETROLEUM COMPANY | 2001-05-15 | — | — | US | disclosed |