SCHEMBL2748466

SCHEMBL2748466

Nc1ccc(Oc2ccc(Oc3ccc(N)c(O)c3)c(C#Cc3ccccc3)c2)cc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 7/20 0.42
MAPT P10636 2/20 0.41
NPC1 O15118 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.38
PTPN1 P18031 1/20 0.37
PTPN11 Q06124 1/20 0.37
MMP2 P08253 1/20 0.35
MMP14 P50281 1/20 0.35
NR4A1 P22736 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2746914 0.90 MAPT (0.42) HAO1MAPTNPC1KDM4EMEN1
SCHEMBL2747732 0.81 MAPT (0.41) HAO1MAPTNPC1KDM4EMEN1
SCHEMBL2747066 0.80 NPC1 (0.41) HAO1MAPTNPC1KDM4EMEN1
SCHEMBL2747566 0.79 ASIC3 (0.41) HAO1MAPTCYP1A2CYP3A4CYP2C9
SCHEMBL2747603 0.79 NR4A1 (0.40) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL2747148 0.78 GAA (0.37) HAO1MAPTNPC1KDM4EMEN1
SCHEMBL2747297 0.77 GAA (0.38) HAO1MAPTNPC1KDM4EMEN1
SCHEMBL2747117 0.76 MAPT (0.41) HAO1MAPTNPC1KDM4EMEN1
SCHEMBL564952 0.76 LTA4H (0.59) MAPTNPC1KDM4EMEN1ALDH1A1
SCHEMBL30233344 0.76 LTA4H (0.59) MAPTNPC1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
US-8178631-B2 Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
US-20090214860-A1 Resin Composition, Varnish, Resin Film and Semiconductor Device SUMITOMO BAKELITE COMPANY, LTD. (JP) 2009-08-27 US disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
EP-1953181-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Ltd. (JP) 2008-08-06 EP disclosed
US-20080044664-A1 Laminated Body and Semiconductor Drive JSR CORPORATION (JP) 2008-02-21 US disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
EP-1760774-A1 LAMINATED BODY AND SEMICONDUCTOR DEVICE JSR Corporation (JP) 2007-03-07 EP disclosed