Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.59 |
| ▸ | THRA | P10827 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | PTPRB | P23467 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | PTEN | P60484 | 1/20 | 0.50 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586 | 0.92 | FFAR1 (0.68) | FFAR1FFAR4THRATHRBESR1 | |
| Trifluoroacetic Acid SCHEMBL27561830 | 0.83 | L3MBTL1 (0.47) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL1445967 | 0.81 | HDAC3 (0.63) | FFAR1FFAR4THRATHRBESR1 | |
| Phenyl Propionic Acid SCHEMBL27428011 | 0.81 | KEAP1 (0.79) | FFAR1FFAR4KEAP1 | |
| SCHEMBL29676744 | 0.80 | MAPT (0.62) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL2067295 | 0.80 | MAPT (0.62) | FFAR1FFAR4THRATHRBESR1 | |
| Trifluoroacetic Acid SCHEMBL27529274 | 0.80 | FFAR1 (0.61) | FFAR1FFAR4KEAP1PPARD | |
| Trifluoroacetic Acid SCHEMBL5657671 | 0.79 | EGFR (0.46) | FFAR1FFAR4THRATHRBESR1 | |
| SCHEMBL7332798 | 0.79 | TAAR1 (0.57) | FFAR1FFAR4THRATHRBESR1 | |
| Phenyl Propionic Acid SCHEMBL27403516 | 0.79 | KEAP1 (0.76) | FFAR1FFAR4KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201454-A | Meta-guanidino, ureido, thioureido or azacyclic aminobenzoic acid derivatives as integrin antagonists | SEARLE & CO (US) | 1998-12-09 | — | — | CN | disclosed |