Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5376966 | 0.88 | DAGLA (0.43) | HSD17B10TLR9MEN1HSP90AA1KMT2A | |
| SCHEMBL9550226 | 0.81 | LMNA (0.46) | LMNAALDH1A1OPRK1TSHRSMN1; SMN2 | |
| SCHEMBL9502987 | 0.81 | ALDH1A1 (0.48) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL10510171 | 0.80 | DPP4 (0.39) | LMNAALDH1A1KMT2AMGLLSMN1; SMN2 | |
| SCHEMBL9492475 | 0.79 | MGLL (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL11375462 | 0.78 | DPP4 (0.36) | LMNAHSD17B10ALDH1A1MGLLTSHR | |
| SCHEMBL8815291 | 0.78 | LMNA (0.42) | LMNAHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL9544526 | 0.76 | DPP4 (0.40) | LMNAALDH1A1KMT2AMGLLSMN1; SMN2 | |
| SCHEMBL9015551 | 0.76 | DPP4 (0.40) | LMNAALDH1A1KMT2AMGLLSMN1; SMN2 | |
| SCHEMBL4897442 | 0.76 | DPP4 (0.37) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363915-A | PRE-EMERGENT | GULF OIL CORPORATION (US) | 1982-12-14 | — | — | US | claimed |
| EP-0045566-A2 | Benzylsulfonyl diethylcarbamyl triazole and use as a selective herbicide | Gulf Oil Corporation (US) | 1982-02-10 | — | — | EP | claimed |
| US-4280831-A | Benzylsulfonyl diethylcarbamyl triazole and use as a selective herbicide | GULF OIL CORPORATION (US) | 1981-07-28 | — | — | US | claimed |
| JP-57058675-A | — | — | None | — | — | JP | disclosed |
| US-7238720-B2 | Pharmaceutical use of N-carbamoylazole derivatives | EISAI R & D MANAGEMENT CO. LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| US-7238720-B2 | Pharmaceutical use of N-carbamoylazole derivatives | EISAI R & D MANAGEMENT CO. LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| EP-1258480-B1 | Pharmaceutical use of N-Carbamoylazole derivatives | EISAI CO LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| EP-1258480-B1 | Pharmaceutical use of N-Carbamoylazole derivatives | EISAI CO LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20040186153-A1 | Pharmaceutical use of N-carbamoylazole derivatives | EISAI R & D MANAGEMENT CO. LTD. (JP) | 2004-09-23 | — | — | US | disclosed |
| US-20030060494-A1 | Pharmaceutical use of N-carbamoylazole derivatives | EISAI CO., LTD. (JP) | 2003-03-27 | — | — | US | disclosed |
| EP-1258480-A1 | Pharmaceutical use of N-Carbamoylazole derivatives | Eisai Co., Ltd. (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-6461997-B1 | SUCH AS 3-(BROMODIFLUOROMETHYLSULFONYL)-1-(N,N-DIETHYL-CARBAMOYL)-1,2,4-TRIAZOLE; SELECTIVITY FOR WEEDS OVER CROPS; APPLY TO PLANTS OR SOIL | MONSANTO TECHNOLOGY LLC | 2002-10-08 | — | — | US | disclosed |
| US-5258361-A | Antigrowth agents biological | ROHM AND HAAS COMPANY (US) | 1993-11-02 | — | — | US | disclosed |
| US-5211739-A | Herbicidal-1-(disubstituted carbamoyl or thiocarbamoyl)-1,2,4-triazol-3-yl sulfonates and thisulfonates | ROHM AND HAAS COMPANY (US) | 1993-05-18 | — | — | US | disclosed |
| EP-0140194-B1 | CARBAMOYLTRIAZOLES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-02-01 | — | — | EP | disclosed |
| US-4363915-A | PRE-EMERGENT | GULF OIL CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |
| JP-S5758675-A | HERBICIDAL 3-BENZYLSULFONYL-1-DIETHYLCARBAMOYL- 1,2,4-TRIAZOLE, HERBICIDAL COMPOSITION CONTAINING SAME AND USE | GULF OIL CORP | 1982-04-08 | — | — | JP | disclosed |
| US-4280831-A | Benzylsulfonyl diethylcarbamyl triazole and use as a selective herbicide | GULF OIL CORPORATION (US) | 1981-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186153-A1 | Pharmaceutical use of N-carbamoylazole derivatives | DPP4, DPP3, DPP7 | LMNA 4734/4885HSD17B10 1300/4885ALDH1A1 1026/4885 |
| US-20030060494-A1 | Pharmaceutical use of N-carbamoylazole derivatives | DPP4, DPP3, DPP7 | LMNA 4734/4885HSD17B10 1300/4885ALDH1A1 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.