Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.65 |
| ▸ | RPA1 | P27694 | 2/20 | 0.65 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236666 | 0.90 | RPA1 (0.72) | PTGS2PTGS1RPA1ALOX5CA9 | |
| SCHEMBL3873219 | 0.89 | CHRNA7 (0.80) | PTGS2RPA1CHRNA7SMN1; SMN2 | |
| SCHEMBL27485627 | 0.89 | PTGS2 (0.69) | PTGS2PTGS1RPA1CHRNA7ALOX5 | |
| SCHEMBL5430032 | 0.89 | CA9 (0.74) | PTGS2PTGS1RPA1CHRNA7ALOX5 | |
| SCHEMBL5698710 | 0.89 | PTGS2 (0.76) | PTGS2PTGS1CHRNA7ALOX5 | |
| SCHEMBL27337910 | 0.89 | RPA1 (0.63) | PTGS2RPA1CHRNA7ALOX5SMN1; SMN2 | |
| SCHEMBL27499348 | 0.86 | CA9 (0.78) | PTGS2PTGS1RPA1CHRNA7ALOX5 | |
| SCHEMBL27554183 | 0.86 | CHRNA7 (0.78) | PTGS2PTGS1RPA1CHRNA7SMN1; SMN2 | |
| SCHEMBL6341643 | 0.86 | PTGS2 (0.82) | PTGS2PTGS1CHRNA7SMN1; SMN2CA9 | |
| SCHEMBL28294492 | 0.86 | CHRNA7 (0.77) | PTGS2PTGS1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1202828-A | Substituted pyrzolyl benzenesulfonanides for use in veterinary | SEARLE & CO (US) | 1998-12-23 | — | — | CN | disclosed |