Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512039 | 0.89 | ALDH1A1 (0.54) | ALDH1A1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL17119639 | 0.78 | SMARCA2 (0.42) | ADRA2AADRA2BADRA2CADRA1APTGS1 | |
| SCHEMBL28103239 | 0.77 | CA12 (0.50) | LMNA | |
| SCHEMBL3645303 | 0.74 | AOC1 (0.49) | PTGS1PTGS2 | |
| SCHEMBL13387995 | 0.73 | KDM4C (0.39) | ALDH1A1LMNARAB9A | |
| SCHEMBL29956744 | 0.71 | TSHR (0.42) | ALDH1A1HTTRAB9A | |
| SCHEMBL14003573 | 0.71 | RAD52 (0.52) | ALDH1A1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL2600757 | 0.71 | KMT2A (0.46) | ALDH1A1LMNA | |
| SCHEMBL29955436 | 0.71 | KMT2A (0.46) | ALDH1A1LMNA | |
| SCHEMBL17461539 | 0.69 | RAB9A (0.52) | ALDH1A1PTGS1PTGS2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1187090-C | Preventives/remedies for interstitial pneumonia and pulmonary fibrosis | MITSUBISHI CHEM CORP (JP) | 2005-02-02 | — | — | CN | disclosed |
| CN-1351504-A | Prophylactic and therapeutic agent for interstitial pneumonia and pulmonary fibrosis | YOSHITOMI PHARMACEUTICAL (JP) | 2002-05-29 | — | — | CN | disclosed |