Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450620 | 0.84 | HTT (0.59) | ALDH1A1TSHRALOX15NAMPTKDM4E | |
| SCHEMBL265014 | 0.84 | ALDH1A1 (0.62) | ALDH1A1TSHRKDM4EATMMEN1 | |
| Hydrochloric Acid SCHEMBL5883332 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4EATMMEN1 | |
| Hydrochloric Acid SCHEMBL380091 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4EATMMEN1 | |
| SCHEMBL7587070 | 0.81 | HDAC1 (0.65) | ALDH1A1TSHRALOX15KDM4EATM | |
| SCHEMBL1571543 | 0.81 | CYP2A6 (0.54) | ALDH1A1TSHRALOX15NTRK1CYP2C9 | |
| SCHEMBL29450607 | 0.80 | NAMPT (0.62) | ALDH1A1TSHRADRA2CNAMPTKDM4E | |
| SCHEMBL29450631 | 0.79 | HCRTR2 (0.49) | ALDH1A1TSHRALOX15ADRA2CNAMPT | |
| Bromomethane SCHEMBL5883760 | 0.79 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4ENPC1RAB9A | |
| SCHEMBL29666526 | 0.78 | ADRA2C (0.55) | ALDH1A1TSHRALOX15ADRA2CNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1152015-C | Piperazine devivatives and process for preparation thereof | ������ҩ��ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| CN-1196724-A | Novel piperazine derivative and process for producing the same | SAMJIN PHARM CO LTD (KR) | 1998-10-21 | — | — | CN | disclosed |