Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.31 |
| ▸ | IP6K3 | Q96PC2 | 3/20 | 0.31 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484414 | 0.88 | HCAR2 (0.33) | — | |
| SCHEMBL27502713 | 0.85 | HSD11B1 (0.38) | CCR2ALDH1A1KDM4EMAPTBACE1 | |
| SCHEMBL27502712 | 0.85 | LPAR1 (0.38) | IP6K1IP6K3IP6K2ALDH1A1HTT | |
| SCHEMBL27554955 | 0.83 | CCNC (0.34) | SLC6A4SLC6A3KDM4ELMNA | |
| SCHEMBL27502711 | 0.82 | HSD11B1 (0.41) | SLC6A2SLC6A4SLC6A3ALDH1A1BACE1 | |
| SCHEMBL27529131 | 0.80 | ALDH1A1 (0.48) | ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL27502325 | 0.79 | MEN1 (0.35) | SLC6A2SLC6A4SLC6A3ALDH1A1LMNA | |
| SCHEMBL27504121 | 0.77 | HSD11B1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL27504464 | 0.77 | HSD11B1 (0.35) | ALDH1A1MAPTGAALMNA | |
| SCHEMBL27503047 | 0.75 | CRHBP (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1196721-A | Heteroaryl-substituted acryloylguanidine derivatives and medicinal composition thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1998-10-21 | — | — | CN | disclosed |