Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 3/20 | 0.45 |
| ▸ | FLT1 | P17948 | 2/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27467102 | 0.89 | SMN1; SMN2 (0.54) | ALDH1A1HTTNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL27486254 | 0.89 | SMN1; SMN2 (0.53) | ALDH1A1HTTNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL27465575 | 0.88 | P2RX1 (0.50) | ALDH1A1HTTNPSR1CYP1A2CYP3A4 | |
| SCHEMBL27486256 | 0.88 | KDR (0.57) | ALDH1A1MAPTSMN1; SMN2LMNANPC1 | |
| SCHEMBL27485248 | 0.84 | KDR (0.59) | ALDH1A1HTTNPSR1CYP3A4TDP1 | |
| SCHEMBL27485244 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HTTNPSR1CYP1A2CYP3A4 | |
| SCHEMBL27468045 | 0.82 | KDR (0.44) | ALDH1A1HTTNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL27484538 | 0.81 | CYP17A1 (0.56) | ALDH1A1HTTNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL27548625 | 0.81 | KDR (0.59) | ALDH1A1MAPTSMN1; SMN2KDRFLT1 | |
| SCHEMBL27485938 | 0.81 | PRKCI (0.53) | MAPTSMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1578768-A | Anthranilamides and pharmaceutical use thereof | NOVARTIS AG (CH) | 2005-02-09 | — | — | CN | claimed |
| CN-100467450-C | Anthranilamides and pharmaceutical use thereof | NOVARTIS AG (CH) | 2009-03-11 | — | — | CN | disclosed |
| CN-1578768-A | Anthranilamides and pharmaceutical use thereof | NOVARTIS AG (CH) | 2005-02-09 | — | — | CN | disclosed |