SCHEMBL27486325

SCHEMBL27486325

COc1cccc(OC)c1C(=O)c1cc[c]cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43
MAPT P10636 4/20 0.42
ALDH1A1 P00352 1/20 0.42
HTT P42858 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.41
TP53 P04637 1/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9467809 0.82 CA12 (0.67) CA12CA1CA2CA7CA9
SCHEMBL5685431 0.82 STS (0.56) RAB9ASMN1; SMN2NPC1KMT2ANPSR1
SCHEMBL27486328 0.82 NPC1 (0.50) SMN1; SMN2NPC1MEN1KMT2ANPSR1
SCHEMBL11755425 0.82 CA1 (0.71) CA12CA1CA2CA7CA9
SCHEMBL29851511 0.81 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL27627508 0.75 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL27498763 0.75 ALDH1A1 (0.38) SMN1; SMN2MEN1KMT2ANPSR1ALDH1A1
SCHEMBL4826226 0.74 CYP1A2 (0.75) CA12CA1CA2CA7CA9
SCHEMBL2888674 0.74 CES2 (0.61) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL10628087 0.74 CA12 (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459692-B Adhesive sheet 日东电工株式会社 2018-03-20 CN disclosed
CN-107636499-A The polarizing coating and image display device of the subsidiary adhesive phase in two sides 日东电工株式会社 2018-01-26 CN disclosed
CN-105555895-B Adhesive sheet 日东电工株式会社 2017-10-27 CN disclosed
CN-106459692-A Adhesive sheet 日东电工株式会社 2017-02-22 CN disclosed
CN-104185468-B The dental binding agent of one pack system 可乐丽则武齿科株式会社 2016-10-12 CN disclosed
CN-1200943-C Organometallic acyl-aryl phosphine CIBA SC HOLDING AG (CH) 2005-05-11 CN disclosed
CN-1308081-A Organometallic acyl-aryl phosphine CIBA SC HOLDING AG (CH) 2001-08-15 CN disclosed