Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16361067 | 0.82 | KDM4E (0.63) | LMNAKDM4ETDP1MAPTHTT | |
| SCHEMBL29101050 | 0.80 | LMNA (0.66) | LMNAKDM4ETDP1MAPTHTT | |
| Sulfuric Acid SCHEMBL11132378 | 0.79 | LMNA (0.79) | LMNAKDM4ETDP1MAPTHTT | |
| SCHEMBL170181 | 0.77 | LMNA (0.61) | LMNAKDM4ETDP1MAPTHTT | |
| SCHEMBL11401809 | 0.75 | LMNA (0.54) | LMNAKDM4ETDP1MAPTHTT | |
| SCHEMBL12853122 | 0.74 | LMNA (0.61) | LMNAKDM4ETDP1MAPTHTT | |
| SCHEMBL12853125 | 0.74 | LMNA (0.61) | LMNAKDM4ETDP1MAPTHTT | |
| SCHEMBL18774829 | 0.74 | CCR1 (0.65) | LMNAKDM4ETDP1MAPTHTT | |
| SCHEMBL7555958 | 0.74 | LMNA (0.56) | LMNAKDM4ETDP1MAPTHTT | |
| SCHEMBL28822835 | 0.74 | LMNA (0.56) | LMNAKDM4ETDP1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1182737-A | New 2-(1H) -quinolinone compounds, process for preparing them and pharmaceutical compositions containing them | ADIR (FR) | 1998-05-27 | — | — | CN | disclosed |